Mecillinam activity against multidrug-resistant Shigella sonnei and Shigella flexneri

Mecillinam activity against multidrug-resistant Shigella sonnei and Shigella flexneri

ABSTRACT We performed phenotypic susceptibility testing and whole-genome sequencing to investigate in vitro mecillinam activity against multidrug-resistant (MDR) Shigella. Ninety-five isolates (53 [56%] Shigella sonnei and 42 [44%] Shigella flexneri) were included. The MIC50 and MIC90 were 1 and 2 µ...

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Bibliographic Details
Main Authors: Aleksandra Stefanovic, Leah Gowland, Gordon Ritchie, Colin Lee, Sam Chorlton, Nancy Matic, Victor Leung, Michael Payne, Christopher F. Lowe, Marc G. Romney
Format: Article
Language:English
Published: American Society for Microbiology 2025-03-01
Series:Microbiology Spectrum
Subjects:
mecillinam
multidrug resistance
Shigella
pivmecillinam
antimicrobial resistance
diarrhea
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01006-24

Internet

https://journals.asm.org/doi/10.1128/spectrum.01006-24

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