Accumbal-thalamic connectivity and associated glutamate alterations in human cocaine craving: A state-dependent rs-fMRI and 1H-MRS study

Accumbal-thalamic connectivity and associated glutamate alterations in human cocaine craving: A state-dependent rs-fMRI and 1H-MRS study

Craving is a core symptom of cocaine use disorder and a major factor for relapse risk. To date, there is no pharmacological therapy to treat this disease or at least to alleviate cocaine craving as a core symptom. In animal models, impaired prefrontal-striatal signalling leading to altered glutamate...

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Bibliographic Details
Main Authors: Etna J.E. Engeli, Andrea G. Russo, Sara Ponticorvo, Niklaus Zoelch, Andreas Hock, Lea M. Hulka, Matthias Kirschner, Katrin H. Preller, Erich Seifritz, Boris B. Quednow, Fabrizio Esposito, Marcus Herdener
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:NeuroImage: Clinical
Subjects:
Cocaine craving
Nucleus accumbens
Prefrontal cortex
Thalamus
Functional connectivity
Glutamate
Online Access:http://www.sciencedirect.com/science/article/pii/S221315822300181X

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http://www.sciencedirect.com/science/article/pii/S221315822300181X

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