An activation specific anti-Mac-1 designed ankyrin repeat protein improves survival in a mouse model of acute lung injury

Abstract The acute respiratory distress syndrome (ARDS) is a life-threatening clinical condition. The number of ARDS cases has risen dramatically recently but specific treatment options are limited. ARDS is associated with an overshooting inflammatory response and neutrophils play a central role in...

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Bibliographic Details
Main Authors: Patrick M. Siegel, Anne-Sophie Przewosnik, Jan Wrobel, Timo Heidt, Martin Moser, Karlheinz Peter, Christoph Bode, Philipp Diehl, István Bojti
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10090-6