Development of Polymersomes Co-Delivering Doxorubicin and Melittin to Overcome Multidrug Resistance

Multidrug resistance (MDR) is one of the major barriers in chemotherapy. It is often related to the overexpression of efflux receptors such as P-glycoprotein (P-gp). Overexpressed efflux receptors inhibit chemotherapeutic efficacy by pumping out intracellularly delivered anticancer drugs. In P-gp-me...

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Bibliographic Details
Main Authors: Eunkyung Han, Doyeon Kim, Youngheun Cho, Seonock Lee, Jungho Kim, Hyuncheol Kim
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/3/1087