Liver afferents contribute to water drinking-induced sympathetic activation in human subjects: a clinical trial.

Water drinking acutely increases sympathetic activity in human subjects. In animals, the response appears to be mediated through transient receptor potential channel TRPV4 activation on osmosensitive hepatic spinal afferents, described as osmopressor response. We hypothesized that hepatic denervatio...

Full description

Bibliographic Details
Main Authors: Marcus May, Faikah Gueler, Hannelore Barg-Hock, Karl-Heinz Heiringhoff, Stefan Engeli, Karsten Heusser, André Diedrich, André Brandt, Christian P Strassburg, Jens Tank, Fred C G J Sweep, Jens Jordan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3189227?pdf=render