A new model for pore formation by cholesterol-dependent cytolysins.

A new model for pore formation by cholesterol-dependent cytolysins.

Cholesterol Dependent Cytolysins (CDCs) are important bacterial virulence factors that form large (200-300 Å) membrane embedded pores in target cells. Currently, insights from X-ray crystallography, biophysical and single particle cryo-Electron Microscopy (cryo-EM) experiments suggest that soluble m...

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Bibliographic Details
Main Authors: Cyril F Reboul, James C Whisstock, Michelle A Dunstone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4140638?pdf=render

Internet

http://europepmc.org/articles/PMC4140638?pdf=render

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