Activation of the Wnt/β-catenin/CYP1B1 pathway alleviates oxidative stress and protects the blood-brain barrier under cerebral ischemia/reperfusion conditions

Activation of the Wnt/β-catenin/CYP1B1 pathway alleviates oxidative stress and protects the blood-brain barrier under cerebral ischemia/reperfusion conditions

Accumulating evidence suggests that oxidative stress and the Wnt/β-catenin pathway participate in stroke-induced disruption of the blood-brain barrier. However, the potential links between them following ischemic stroke remain largely unknown. The present study found that cerebral ischemia leads to...

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Bibliographic Details
Main Authors: Xingyong Chen, Nannan Yao, Yanguang Mao, Dongyun Xiao, Yiyi Huang, Xu Zhang, Yinzhou Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Neural Regeneration Research
Subjects:
blood-brain barrier; cyp1b1; oxidative stress; oxygen glucose deprivation/reoxygenation; tight junction; vascular endothelial cells; wnt/β-catenin pathway; β-catenin
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=7;spage=1541;epage=1547;aulast=Chen

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=7;spage=1541;epage=1547;aulast=Chen

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