Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes

Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes

Objective: Serum concentrations of the hepatokine fibroblast growth factor (FGF) 21 are elevated in obesity, type-2 diabetes, and the metabolic syndrome. We asked whether FGF21 levels differ between subjects with metabolically healthy vs. unhealthy obesity (MHO vs. MUHO), opening the possibility tha...

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Bibliographic Details
Main Authors: Lucia Berti, Martin Irmler, Marty Zdichavsky, Tobias Meile, Anja Böhm, Norbert Stefan, Andreas Fritsche, Johannes Beckers, Alfred Königsrainer, Hans-Ulrich Häring, Martin Hrabě de Angelis, Harald Staiger
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Molecular Metabolism
Subjects:
FGF21
Hepatokine
Adiponectin
Adipokine
Secretome
Type-2 diabetes
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877815000745

Internet

http://www.sciencedirect.com/science/article/pii/S2212877815000745

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