Bruton’s tyrosine kinase is a possible therapeutic target in microscopic polyangiitis

Bruton’s tyrosine kinase is a possible therapeutic target in microscopic polyangiitis

Abstract Background Bruton’s tyrosine kinase (Btk) is an enzyme expressed in leukocytes other than T lymphocytes and plasma cells and involved in B-cell receptor- and Fcγ receptor (FcγR)-mediated signal transduction. Btk inhibitors potentially suppress autoantibody production due to the expected inh...

Full description

Bibliographic Details
Main Authors: Issei Nakade, Yuto Tamura, Fuyu Hashimoto, Yuko Ariza, Shingo Hotta, Hirofumi Fujigaya, Suishin Arai, Mai Taniguchi, Hodaka Ogawa, Yuka Nishibata, Sakiko Masuda, Daigo Nakazawa, Utano Tomaru, Akihiro Ishizu
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Arthritis Research & Therapy
Subjects:
MPO-ANCA
MPA
NETs
Btk
Btk inhibitor
Tirabrutinib
Online Access:https://doi.org/10.1186/s13075-023-03201-9

Internet

https://doi.org/10.1186/s13075-023-03201-9

Similar Items