15-Lipoxygenase promotes resolution of inflammation in lymphedema by controlling Treg cell function through IFN-β

15-Lipoxygenase promotes resolution of inflammation in lymphedema by controlling Treg cell function through IFN-β

Abstract Lymphedema (LD) is characterized by the accumulation of interstitial fluid, lipids and inflammatory cell infiltrate in the limb. Here, we find that LD tissues from women who developed LD after breast cancer exhibit an inflamed gene expression profile. Lipidomic analysis reveals decrease in...

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Bibliographic Details
Main Authors: A. Zamora, M. Nougué, L. Verdu, E. Balzan, T. Draia-Nicolau, E. Benuzzi, F. Pujol, V. Baillif, E. Lacazette, F. Morfoisse, J. Galitzky, A. Bouloumié, M. Dubourdeau, B. Chaput, N. Fazilleau, J. Malloizel-Delaunay, A. Bura-Rivière, A. C. Prats, B. Garmy-Susini
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43554-y

Internet

https://doi.org/10.1038/s41467-023-43554-y

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