Non-Vesicular Release of Alarmin Prothymosin α Complex Associated with Annexin-2 Flop-Out

Nuclear protein prothymosin α (ProTα) is a unique member of damage-associated molecular patterns (DAMPs)/alarmins. ProTα prevents neuronal necrosis by causing a cell death mode switch in serum-starving or ischemic/reperfusion models in vitro and in vivo. Underlying receptor mechanisms include Toll-l...

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Bibliographic Details
Main Author: Hiroshi Ueda
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/12/1569