The Immune Checkpoint Receptor CD96: A Local and Systemic Immune Modulator in Oral Cancer?

The Immune Checkpoint Receptor CD96: A Local and Systemic Immune Modulator in Oral Cancer?

<b>Background</b>: As immunotherapy of oral squamous cell carcinomas (OSCCs), using PD1 inhibitors, is only efficient in a small proportion of patients, additional immune checkpoints need to be identified as potential therapeutic targets. There is evidence that a blockade of CD96 might p...

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Bibliographic Details
Main Authors: Leah Trumet, Manuel Weber, Alina Hahn, Lina Kunater, Carol Geppert, Jacek Glajzer, Ann-Kristin Struckmeier, Tobias Möst, Rainer Lutz, Marco Kesting, Jutta Ries
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cancers
Subjects:
immune checkpoints
immunotherapy
OSCC
HNSCC
PD-1
PD-L1
Online Access:https://www.mdpi.com/2072-6694/15/7/2126

Internet

https://www.mdpi.com/2072-6694/15/7/2126

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