Impact of gallstone disease on the risk of stroke and coronary artery disease: evidence from prospective observational studies and genetic analyses

Impact of gallstone disease on the risk of stroke and coronary artery disease: evidence from prospective observational studies and genetic analyses

Abstract Background Despite epidemiological evidence associating gallstone disease (GSD) with cardiovascular disease (CVD), a dilemma remains on the role of cholecystectomy in modifying the risk of CVD. We aimed to characterize the phenotypic and genetic relationships between GSD and two CVD events...

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Bibliographic Details
Main Authors: Li Zhang, Wenqiang Zhang, Lin He, Huijie Cui, Yutong Wang, Xueyao Wu, Xunying Zhao, Peijing Yan, Chao Yang, Changfeng Xiao, Mingshuang Tang, Lin Chen, Chenghan Xiao, Yanqiu Zou, Yunjie Liu, Yanfang Yang, Ling Zhang, Yuqin Yao, Jiayuan Li, Zhenmi Liu, Chunxia Yang, Xia Jiang, Ben Zhang
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Medicine
Subjects:
Gallstone disease
Cardiovascular disease
Phenotypic association
Genetic correlation
Mendelian randomization
Online Access:https://doi.org/10.1186/s12916-023-03072-6

Internet

https://doi.org/10.1186/s12916-023-03072-6

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