Defining reference sequences for Nocardia species by similarity and clustering analyses of 16S rRNA gene sequence data.

BACKGROUND: The intra- and inter-species genetic diversity of bacteria and the absence of 'reference', or the most representative, sequences of individual species present a significant challenge for sequence-based identification. The aims of this study were to determine the utility, and co...

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Bibliographic Details
Main Authors: Manal Helal, Fanrong Kong, Sharon C A Chen, Michael Bain, Richard Christen, Vitali Sintchenko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3110597?pdf=render