CRISPR-Cas systems target endogenous genes to impact bacterial physiology and alter mammalian immune responses

CRISPR-Cas systems target endogenous genes to impact bacterial physiology and alter mammalian immune responses

Abstract CRISPR-Cas systems are an immune defense mechanism that is widespread in archaea and bacteria against invasive phages or foreign genetic elements. In the last decade, CRISPR-Cas systems have been a leading gene-editing tool for agriculture (plant engineering), biotechnology, and human healt...

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Bibliographic Details
Main Authors: Qun Wu, Luqing Cui, Yingying Liu, Rongpeng Li, Menghong Dai, Zhenwei Xia, Min Wu
Format: Article
Language:English
Published: Springer 2022-07-01
Series:Molecular Biomedicine
Subjects:
Inflammasome
Host immune response
Endogenous gene targeting
Phagocytosis
Biofilms
Inflammatory response
Online Access:https://doi.org/10.1186/s43556-022-00084-1

Internet

https://doi.org/10.1186/s43556-022-00084-1

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