TREM2 Regulates the Removal of Apoptotic Cells and Inflammatory Processes during the Progression of NAFLD

TREM2 Regulates the Removal of Apoptotic Cells and Inflammatory Processes during the Progression of NAFLD

Nonalcoholic fatty liver disease (NAFLD) is the most common liver pathology worldwide. In mice and humans, NAFLD progression is characterized by the appearance of TREM2-expressing macrophages in the liver. However, their mechanistic contributions to disease progression have not been completely eluci...

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Bibliographic Details
Main Authors: Imke Liebold, Simon Meyer, Markus Heine, Anastasia Kuhl, Jennifer Witt, Leah Eissing, Alexander W. Fischer, Anja Christina Koop, Johannes Kluwe, Julian Schulze zur Wiesch, Malte Wehmeyer, Uwe Knippschild, Ludger Scheja, Joerg Heeren, Lidia Bosurgi, Anna Worthmann
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cells
Subjects:
nonalcoholic fatty liver disease (NAFLD)
nonalcoholic steatohepatitis (NASH)
metabolic-associated fatty liver disease (MAFLD)
macrophages
TREM2
phagocytosis
Online Access:https://www.mdpi.com/2073-4409/12/3/341

Internet

https://www.mdpi.com/2073-4409/12/3/341

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