FISH Diagnostic Assessment of <i>MDM2</i> Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting Recommendations

FISH Diagnostic Assessment of <i>MDM2</i> Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting Recommendations

<i>MDM2</i> amplification represents the leading oncogenic pathway and diagnostic hallmark of liposarcoma, whose assessment is based on Fluorescence In Situ Hybridization (FISH) analysis. Despite its diagnostic relevance, no univocal interpretation criteria regarding FISH assessments of...

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Bibliographic Details
Main Authors: Alessandro Gambella, Luca Bertero, Milena Rondón-Lagos, Ludovica Verdun Di Cantogno, Nelson Rangel, Chiara Pitino, Alessia Andrea Ricci, Luca Mangherini, Isabella Castellano, Paola Cassoni
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
<i>MDM2</i> amplification
liposarcoma
FISH
<i>MDM2</i> interpretation guidelines
Online Access:https://www.mdpi.com/1422-0067/24/2/1342

Internet

https://www.mdpi.com/1422-0067/24/2/1342

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