Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3

Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3

Abstract The t(14;19)(q32;q13) is a rare recurring translocation found in B-cell lymphoproliferative malignancies, involving the Bcl-3 gene. This chromosomal translocation is often found in patients under the age of 50 and causes a more progressive disease. The Bcl-3 gene encodes a protein belonging...

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Bibliographic Details
Main Authors: Renée Daams, Thi Thu Phuong Tran, Mohamed Jemaà, Wondossen Sime, Ruta Mickeviciute, Sara Ek, Lars Rönnstrand, Julhash U. Kazi, Ramin Massoumi
Format: Article
Language:English
Published: Nature Publishing Group 2024-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07067-w

Internet

https://doi.org/10.1038/s41419-024-07067-w

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