Genetic diversity of EBV-encoded LMP1 in the Swiss HIV Cohort Study and implication for NF-Κb activation.

Epstein-Barr virus (EBV) is associated with several types of cancers including Hodgkin's lymphoma (HL) and nasopharyngeal carcinoma (NPC). EBV-encoded latent membrane protein 1 (LMP1), a multifunctional oncoprotein, is a powerful activator of the transcription factor NF-κB, a property that is e...

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Main Authors: Emilie Zuercher, Christophe Butticaz, Josiane Wyniger, Raquel Martinez, Manuel Battegay, Emmanuelle Boffi El Amari, Thanh Dang, Jean-François Egger, Jan Fehr, Esther Mueller-Garamvögyi, Andrea Parini, Stephan C Schaefer, Franziska Schoeni-Affolter, Christine Thurnheer, Marianne Tinguely, Amalio Telenti, Sylvia Rothenberger, Swiss HIV Cohort Study
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3285206?pdf=render