Intracranial Gene Delivery Mediated by Albumin-Based Nanobubbles and Low-Frequency Ultrasound

Research in the field of high-intensity focused ultrasound (HIFU) for intracranial gene therapy has greatly progressed over the years. However, limitations of conventional HIFU still remain. That is, genes are required to cross the blood-brain barrier (BBB) in order to reach the neurological disorde...

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Bibliographic Details
Main Authors: Takayuki Koga, Hiroshi Kida, Yutaro Yamasaki, Loreto B. Feril, Hitomi Endo, Keiji Itaka, Hiroshi Abe, Katsuro Tachibana
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/14/3/285