Mechanisms of structural chromosomal rearrangement formation

Mechanisms of structural chromosomal rearrangement formation

Abstract Structural chromosomal rearrangements result from different mechanisms of formation, usually related to certain genomic architectural features that may lead to genetic instability. Most of these rearrangements arise from recombination, repair, or replication mechanisms that occur after a do...

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Bibliographic Details
Main Authors: Bruna Burssed, Malú Zamariolli, Fernanda Teixeira Bellucco, Maria Isabel Melaragno
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Molecular Cytogenetics
Subjects:
Structural chromosomal rearrangements
Mechanisms of formation
Non-allelic homologous recombination (NAHR)
Non-homologous end-joining (NHEJ)
Fork stalling and template switching (FoSTeS)
Microhomology-mediated break-induced replication (MMBIR)
Online Access:https://doi.org/10.1186/s13039-022-00600-6

Internet

https://doi.org/10.1186/s13039-022-00600-6

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