High-affinity peptides developed against calprotectin and their application as synthetic ligands in diagnostic assays

Abstract Common inflammatory disorders such as ulcerative colitis and Crohn’s disease are non-invasively diagnosed or monitored by the biomarker calprotectin. However, current quantitative tests for calprotectin are antibody-based and vary depending on the type of antibody and assay used. Additional...

Full description

Bibliographic Details
Main Authors: Cristina Díaz-Perlas, Benjamin Ricken, Lluc Farrera-Soler, Dmitrii Guschin, Florence Pojer, Kelvin Lau, Christian-Benedikt Gerhold, Christian Heinis
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38075-7