Development and immunological evaluation of an mRNA-based vaccine targeting Naegleria fowleri for the treatment of primary amoebic meningoencephalitis

Development and immunological evaluation of an mRNA-based vaccine targeting Naegleria fowleri for the treatment of primary amoebic meningoencephalitis

Abstract More than 95% of patients fall victim to primary amoebic meningoencephalitis (PAM), a fatal disease attacking the central nervous system. Naegleria fowleri, a brain-eating microorganism, is PAM's most well-known pathogenic ameboflagellate. Despite the use of antibiotics, the fatality r...

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Bibliographic Details
Main Authors: Muhammad Naveed, Urooj Ali, Tariq Aziz, Khizra Jabeen, Muhammad Hammad Arif, Metab Alharbi, Abdullah F. Alasmari, Thamer H. Albekairi
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-51127-8

Internet

https://doi.org/10.1038/s41598-023-51127-8

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