Determination of elemental impurities in valproic acid an epilepsy drug by using ICP-MS

Background: According to previously published research, different analytical methods (GC, HPLC, etc.) were used to determine Valproic acid and its Genotoxic impurities. The heavy metals were also attempted to be determined using the ICP-MS technique in other drug substances. Methods: The present wor...

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Bibliographic Details
Main Authors: Satish Ganta, T. Siva Rao, K. Rama Srinivas, Pallapati Suman
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Trace Elements and Minerals
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2773050622000350