Personalized approach to patients with statin intolerance based on pharmacogenomics (function of OATP1B1 protein)

Statins, HMG CoA reductase inhibitors, are effective at lowering blood cholesterol levels and protecting against cardiovascular incidents. Their uptake into hepatocytes depends on the activity of the SLCO1B1 gene which codes for the OATP1B1 transporter protein. Pharmacogenomic testing provides us in...

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Bibliographic Details
Main Authors: Anja Ćuk, Doroteja Đekić, Dunja Leskovar, Livija Šimičević
Format: Article
Language:English
Published: Hrvatski liječnički zbor 2023-01-01
Series:Liječnički vjesnik
Subjects:
Online Access:https://hrcak.srce.hr/file/438252