Personalized approach to patients with statin intolerance based on pharmacogenomics (function of OATP1B1 protein)
Statins, HMG CoA reductase inhibitors, are effective at lowering blood cholesterol levels and protecting against cardiovascular incidents. Their uptake into hepatocytes depends on the activity of the SLCO1B1 gene which codes for the OATP1B1 transporter protein. Pharmacogenomic testing provides us in...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Hrvatski liječnički zbor
2023-01-01
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Series: | Liječnički vjesnik |
Subjects: | |
Online Access: | https://hrcak.srce.hr/file/438252 |