Functional polymorphisms of NOS3 and GUCY1A3 affect both nitric oxide formation and association with hypertensive disorders of pregnancy

Functional polymorphisms of NOS3 and GUCY1A3 affect both nitric oxide formation and association with hypertensive disorders of pregnancy

Impaired nitric oxide (NO) formation may be associated with endothelial dysfunction and increased cardiovascular disease risk in preeclampsia (PE). Functional single-nucleotide polymorphisms (SNPs) of nitric oxide synthase 3 (NOS3) (rs3918226) and guanylate cyclase 1, soluble, alpha 3 (GUCY1A3) (rs7...

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Bibliographic Details
Main Authors: Daniela A. Pereira, Marcelo R. Luizon, Ana C. Palei, José E. Tanus-Santos, Ricardo C. Cavalli, Valeria C. Sandrim
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Genetics
Subjects:
genetic polymorphisms
gestational hypertension
guanylate cyclase 1 soluble alpha 3
nitric oxide
nitric oxide synthase 3
preeclampsia
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1293082/full

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https://www.frontiersin.org/articles/10.3389/fgene.2024.1293082/full

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