Protocol for a multicentre, double-blind, randomised, placebo-controlled trial of riociguat on peak cardiac index during exercise in patients with chronic thromboembolic pulmonary hypertension after balloon pulmonary angioplasty (THERAPY-HYBRID-BPA trial)
Objectives Balloon pulmonary angioplasty (BPA) and medical therapy, such as soluble guanylate cyclase stimulators, are recommended treatments for patients with chronic thromboembolic pulmonary hypertension (CTEPH) who are ineligible for pulmonary endarterectomy (PEA). However, monotherapy with BPA o...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2023-07-01
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Series: | BMJ Open |
Online Access: | https://bmjopen.bmj.com/content/13/7/e072241.full |