Balancing sensitivity and specificity in distinguishing TCR groups by CDR sequence similarity
Abstract Background Repertoire sequencing is enabling deep explorations into the cellular immune response, including the characterization of commonalities and differences among T cell receptor (TCR) repertoires from different individuals, pathologies, and antigen specificities. In seeking to underst...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-05-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-019-2864-8 |