Non-enzymatic lipid peroxidation initiated by photodynamic therapy drives a distinct ferroptosis-like cell death pathway

Non-enzymatic lipid peroxidation initiated by photodynamic therapy drives a distinct ferroptosis-like cell death pathway

Ferroptosis is primarily triggered by a failure of the glutathione (GSH)-glutathione peroxidase 4 (GPX4) reductive system and associated overwhelming lipid peroxidation, in which enzymes regulating polyunsaturated fatty acid (PUFA) metabolism, and in particular acyl-CoA synthetase long chain family...

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Bibliographic Details
Main Authors: Sufang Shui, Zenglu Zhao, Hao Wang, Marcus Conrad, Guoquan Liu
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Redox Biology
Subjects:
Lipid peroxidation
Ferroptosis
Liperoptosis
PDT
Cell death
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721002159

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http://www.sciencedirect.com/science/article/pii/S2213231721002159

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