Molecular Dynamics Simulations of Acetylcholinesterase – Beta-Amyloid Peptide Complex
Alzheimer’s Disease (AD) is a neurodegenerative disorder with severe consequences and lethal outcome. One of the pathological hallmarks of the disease is the formation of insoluble intercellular beta-Amyloid (Aβ) plaques. The enzyme ACetylcholinEsterase (AChE) promotes and accelerates the aggregatio...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2020-12-01
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Series: | Cybernetics and Information Technologies |
Subjects: | |
Online Access: | https://doi.org/10.2478/cait-2020-0068 |