Molecular Dynamics Simulations of Acetylcholinesterase – Beta-Amyloid Peptide Complex

Alzheimer’s Disease (AD) is a neurodegenerative disorder with severe consequences and lethal outcome. One of the pathological hallmarks of the disease is the formation of insoluble intercellular beta-Amyloid (Aβ) plaques. The enzyme ACetylcholinEsterase (AChE) promotes and accelerates the aggregatio...

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Bibliographic Details
Main Authors: Atanasova Mariana, Dimitrov Ivan, Ivanov Stefan
Format: Article
Language:English
Published: Sciendo 2020-12-01
Series:Cybernetics and Information Technologies
Subjects:
Online Access:https://doi.org/10.2478/cait-2020-0068