Mitochondrial variants of complex I genes associated with leprosy clinical subtypes

Mitochondrial variants of complex I genes associated with leprosy clinical subtypes

Abstract Leprosy is a chronic bacterial infection mainly caused by Mycobacterium leprae that primarily affects skin and peripheral nerves. Due to its ability to absorb carbon from the host cell, the bacillus became dependent on energy production, mainly through oxidative phosphorylation. In fact, va...

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Bibliographic Details
Main Authors: Felipe Gouvea de Souza, Caio S. Silva, Gilderlanio S. de Araújo, Mayara N. Santana-da-Silva, Angélica Rita Gobbo, Moisés Batista da Silva, Pablo Pinto, Patrícia Fagundes da Costa, Claudio Guedes Salgado, Ândrea Ribeiro-dos-Santos, Giovanna C. Cavalcante
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Leprosy
Mitochondria
mtDNA
Complex I
Heteroplasmy
Online Access:https://doi.org/10.1038/s41598-024-57191-y

Internet

https://doi.org/10.1038/s41598-024-57191-y

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