F420H2-dependent degradation of aflatoxin and other furanocoumarins is widespread throughout the actinomycetales.

Two classes of F(420)-dependent reductases (FDR-A and FDR-B) that can reduce aflatoxins and thereby degrade them have previously been isolated from Mycobacterium smegmatis. One class, the FDR-A enzymes, has up to 100 times more activity than the other. F(420) is a cofactor with a low reduction poten...

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Bibliographic Details
Main Authors: Gauri V Lapalikar, Matthew C Taylor, Andrew C Warden, Colin Scott, Robyn J Russell, John G Oakeshott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3288000?pdf=render