COVID-19 Molecular Pathophysiology: Acetylation of Repurposing Drugs

COVID-19 Molecular Pathophysiology: Acetylation of Repurposing Drugs

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces immune-mediated type 1 interferon (IFN-1) production, the pathophysiology of which involves sterile alpha motif and histidine-aspartate domain-containing protein 1 (SAMHD1) tetramerization and the cytosolic DNA sensor cyclic-GMP-AM...

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Bibliographic Details
Main Authors: Jong Hoon Lee, Badar Kanwar, Asif Khattak, Jenny Balentine, Ngoc Huy Nguyen, Richard E. Kast, Chul Joong Lee, Jean Bourbeau, Eric L. Altschuler, Consolato M. Sergi, Tuan Ngoc Minh Nguyen, Sangsuk Oh, Mun-Gi Sohn, Michael Coleman
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
ACE2 (angiotensin-converting enzyme 2)
aspirin
cGAS–STING (cyclic guanosine monophosphate (GMP)-adenosine monophosphate (AMP) synthase (cGAS)–stimulator of interferon genes (STING))
dapsone
dexamethasone
immunologic engram
Online Access:https://www.mdpi.com/1422-0067/23/21/13260

Internet

https://www.mdpi.com/1422-0067/23/21/13260

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