In vitro and in silico evaluation of antiretrovirals against SARS-CoV-2: A drug repurposing approach

In vitro and in silico evaluation of antiretrovirals against SARS-CoV-2: A drug repurposing approach

Background: Drug repurposing is a valuable strategy for rapidly developing drugs for treating COVID-19. This study aimed to evaluate the antiviral effect of six antiretrovirals against SARS-CoV-2 in vitro and in silico. Methods: The cytotoxicity of lamivudine, emtricitabine, tenofovir, abacavir...

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Bibliographic Details
Main Authors: Maria I. Zapata-Cardona, Lizdany Florez-Alvarez, Ariadna L. Guerra-Sandoval, Mateo Chvatal-Medina, Carlos M. Guerra-Almonacid, Jaime Hincapie-Garcia, Juan C. Hernandez, Maria T. Rugeles, Wildeman Zapata-Builes
Format: Article
Language:English
Published: AIMS Press 2023-01-01
Series:AIMS Microbiology
Subjects:
antiretrovirals
sars-cov-2
covid-19
molecular docking
drug repurposing
Online Access:https://www.aimspress.com/article/doi/10.3934/microbiol.2023002?viewType=HTML

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https://www.aimspress.com/article/doi/10.3934/microbiol.2023002?viewType=HTML

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