Mutant p53 drives cancer by subverting multiple tumour suppression pathways

The tumour suppressor p53 normally acts as a brake to halt damaged cells from perpetrating their genetic errors into future generations. If p53 is disrupted by mutation, it may not only lose these corrective powers, but counter-productively acquire new capacities that drive cancer. A newly emerging...

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Váldodahkkit: Sue eHaupt, Dinesh eRaghu, Ygal eHaupt
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Frontiers Media S.A. 2016-01-01
Ráidu:Frontiers in Oncology
Fáttát:
Liŋkkat:http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00012/full