Dppa3 facilitates self-renewal of embryonic stem cells by stabilization of pluripotent factors

Dppa3 facilitates self-renewal of embryonic stem cells by stabilization of pluripotent factors

Abstract Background Developmental pluripotency-associated 3 (Dppa3, also called Stella or PGC7) is a principal maternal protein specially expressed in pre-implantation embryos, embryonic stem cells (ES cells) and primordial germ cells (PGCs). It plays critical role in the regulating of DNA methylati...

Full description

Bibliographic Details
Main Authors: Shuang Zhao, Chuanyu Zhang, Jia Xu, Siying Liu, Lu Yu, Shang Chen, Hang Wen, Zongjin Li, Na Liu
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Stem Cell Research & Therapy
Subjects:
Dppa3
Nanog
Degradation
Embryonic stem cells
Online Access:https://doi.org/10.1186/s13287-022-02846-8

Internet

https://doi.org/10.1186/s13287-022-02846-8

Similar Items