Metabolic benefits of methionine restriction in adult mice do not require functional methionine sulfoxide reductase A (MsrA)

Abstract Methionine restriction (MR) extends lifespan and improves several markers of health in rodents. However, the proximate mechanisms of MR on these physiological benefits have not been fully elucidated. The essential amino acid methionine plays numerous biological roles and limiting its availa...

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Bibliographic Details
Main Authors: Kevin M. Thyne, Adam B. Salmon
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08978-4