Improved Solubility of Vortioxetine Using C2-C4 Straight-Chain Dicarboxylic Acid Salt Hydrates
The purpose of this study was to improve the solubility of vortioxetine by crystal engineering principles. In this paper, three C2-C4 straight-chain dicarboxylic acid salt hydrates of vortioxetine (VOT-OA, VOT-MA-H2O, and VOT-SUA-H2O, VOT = vortioxetine, OA = Oxalic acid, MA = malonic acid, SUA = su...
Main Authors: | Lei Gao, Xian-Rui Zhang, Shao-Ping Yang, Juan-Juan Liu, Chao-Jie Chen |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-09-01
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Series: | Crystals |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4352/8/9/352 |
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