Nanopore long-read RNA sequencing reveals functional alternative splicing variants in human vascular smooth muscle cells

Nanopore long-read RNA sequencing reveals functional alternative splicing variants in human vascular smooth muscle cells

Abstract Vascular smooth muscle cells (VSMCs) are the major contributor to vascular repair and remodeling, which showed high level of phenotypic plasticity. Abnormalities in VSMC plasticity can lead to multiple cardiovascular diseases, wherein alternative splicing plays important roles. However, alt...

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Bibliographic Details
Main Authors: Hao Wu, Yicheng Lu, Zhenzhen Duan, Jingni Wu, Minghui Lin, Yangjun Wu, Siyang Han, Tongqi Li, Yuqi Fan, Xiaoyuan Hu, Hongyan Xiao, Jiaxuan Feng, Zhiqian Lu, Deping Kong, Shengli Li
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05481-y

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https://doi.org/10.1038/s42003-023-05481-y

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