Profiling of chromatin accessibility and identification of general cis-regulatory mechanisms that control two ocular lens differentiation pathways

Profiling of chromatin accessibility and identification of general cis-regulatory mechanisms that control two ocular lens differentiation pathways

Abstract Background Promoters and enhancers are cis-regulatory DNA sequences that control specificity and quantity of transcription. Both are rich on clusters of cis-acting sites that interact with sequence-specific DNA-binding transcription factors (TFs). At the level of chromatin, these regions di...

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Bibliographic Details
Main Authors: Yilin Zhao, Deyou Zheng, Ales Cvekl
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Epigenetics & Chromatin
Subjects:
ATAC-seq
Differentiation
Lens
“Open” chromatin
RNA-seq
Tissue specificity
Online Access:http://link.springer.com/article/10.1186/s13072-019-0272-y

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http://link.springer.com/article/10.1186/s13072-019-0272-y

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