Host Defense Peptide-Mimicking Polymers and Polymeric-Brush-Tethered Host Defense Peptides: Recent Developments, Limitations, and Potential Success

Host Defense Peptide-Mimicking Polymers and Polymeric-Brush-Tethered Host Defense Peptides: Recent Developments, Limitations, and Potential Success

Amphiphilic antimicrobial polymers have attracted considerable interest as structural mimics of host defense peptides (HDPs) that provide a broad spectrum of activity and do not induce bacterial-drug resistance. Likewise, surface engineered polymeric-brush-tethered HDP is considered a promising coat...

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Bibliographic Details
Main Authors: Hashem Etayash, Robert E. W. Hancock
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pharmaceutics
Subjects:
host defense peptides
antimicrobial polymers
polymer brush
biofilms
antibiotic resistance
Online Access:https://www.mdpi.com/1999-4923/13/11/1820

Internet

https://www.mdpi.com/1999-4923/13/11/1820

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