Tripeptide IRW Improves AMPK/eNOS Signaling Pathway via Activating ACE2 in the Aorta of High-Fat-Diet-Fed C57BL/6 Mice

This study aims to investigate the effect of tripeptide IRW on the local renin–angiotensin system (RAS), particularly angiotensin-converting enzyme 2 (ACE2), and their association with signaling pathways in the aorta of a high-fat-diet (HFD)-induced insulin-resistant mouse model. C57BL/6 mice were f...

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Bibliographic Details
Main Authors: Fatemeh Ashkar, Khushwant S. Bhullar, Xu Jiang, Jianping Wu
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/12/4/556