Captopril and Valsartan May Improve Cogniti ve Function Through Potentiation of the Brain Antioxidant Defense System and Attenuation of Oxidative/Nitrosative Damage in STZ - Induced Dementia in Rat

Captopril and Valsartan May Improve Cogniti ve Function Through Potentiation of the Brain Antioxidant Defense System and Attenuation of Oxidative/Nitrosative Damage in STZ - Induced Dementia in Rat

Purpose: Previous findings have shown the crucial roles of brain renin-angiotensin system (RAS) in pathogenesis of Alzheimer’s disease (AD). Since RAS inhibitors may have beneficial effects on dementia and cognitive function in elderly people, the aim of present study was to examine the neuroprotect...

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Bibliographic Details
Main Authors: Yasaman Arjmand Abbassi, Mohammad Taghi Mohammadi, Mahsa Sar ami Foroshani, Javad Raouf Sarshoori
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2016-12-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Alzheimer’s disease
Antioxidant
Renin - angiotensin system
Captopril
Valsartan
Online Access:http://journals.tbzmed.ac.ir/APB/Manuscript/APB-6-531.pdf

Internet

http://journals.tbzmed.ac.ir/APB/Manuscript/APB-6-531.pdf

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