Excitatory deep brain stimulation quenches beta oscillations arising in a computational model of the subthalamo-pallidal loop

Abstract Parkinson’s disease (PD) is associated with abnormal $$\beta$$ β band oscillations (13–30 Hz) in the cortico-basal ganglia circuits. Abnormally increased striato-pallidal inhibition and strengthening the synaptic coupling between subthalamic nucleus (STN) and globus pallidus externa (GPe),...

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Bibliographic Details
Main Authors: Seyed Mojtaba Alavi, Amin Mirzaei, Alireza Valizadeh, Reza Ebrahimpour
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10084-4