Excitatory deep brain stimulation quenches beta oscillations arising in a computational model of the subthalamo-pallidal loop
Abstract Parkinson’s disease (PD) is associated with abnormal $$\beta$$ β band oscillations (13–30 Hz) in the cortico-basal ganglia circuits. Abnormally increased striato-pallidal inhibition and strengthening the synaptic coupling between subthalamic nucleus (STN) and globus pallidus externa (GPe),...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-10084-4 |