A new childhood ALL case with an extremely complex karyotype and acute spontaneous tumor lysis syndrome

A new childhood ALL case with an extremely complex karyotype and acute spontaneous tumor lysis syndrome

Abstract Background B cell precursor acute lymphoblastic leukemia (B-ALL) is the most common malignancy of childhood, with, after corresponding treatment, an overall complete remission rate of 90%. Approximately 75% of B-ALL cases harbor recurrent abnormalities, including so-called complex karyotype...

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Bibliographic Details
Main Authors: Abdulsamad Wafa, Rami A. Jarjour, Doaa Alolabi, Thomas Liehr, Othman Hamdan, Joana B. Melo, Isabel M. Carreira, Moneeb A. K. Othman, Walid Al-Achkar
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Molecular Cytogenetics
Subjects:
Acute lymphoblastic leukemia (ALL)
Complex karyotype (CK)
Molecular cytogenetics
Array comparative genomic hybridization (aCGH)
Tumor lysis syndrome (TLS)
Prognostic factors
Online Access:http://link.springer.com/article/10.1186/s13039-020-00512-3

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http://link.springer.com/article/10.1186/s13039-020-00512-3

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