Structural and Functional Changes in Aged Skin Lymphatic Vessels

Structural and Functional Changes in Aged Skin Lymphatic Vessels

Lymphatic structure and function play a critical role in fluid transport, antigen delivery, and immune homeostasis. A dysfunctional lymphatic system is associated with chronic low-grade inflammation of peripheral tissues, poor immune responses, and recurrent infections, which are also hallmarks of a...

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Bibliographic Details
Main Authors: Raghu P. Kataru, Hyeung Ju Park, Jinyeon Shin, Jung Eun Baik, Ananta Sarker, Stav Brown, Babak J. Mehrara
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Aging
Subjects:
dermal lymphatics
age-related lymphatic dysfunction
peri-lymphatic inflammation
lymphatic endothelial apoptosis
decreased LEC VEGFR-3 signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2022.864860/full

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https://www.frontiersin.org/articles/10.3389/fragi.2022.864860/full

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