Molecular Mechanism Analysis of STIM1 Thermal Sensation

STIM1 has been identified as a new warm sensor, but the exact molecular mechanism remains unclear. In this study, a variety of mutants of STIM1, Orai1 and Orai3 were generated. The single–cell calcium imaging and confocal analysis were used to evaluate the thermal sensitivity of the resulting STIM m...

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Bibliographic Details
Main Authors: Xiaoling Liu, Tianyuan Zheng, Yan Jiang, Lei Wang, Yuchen Zhang, Qiyu Liang, Yuejie Chen
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/22/2613