<i>SERPINE1</i> DNA Methylation Levels Quantified in Blood Cells at Five Years of Age Are Associated with Adiposity and Plasma PAI-1 Levels at Five Years of Age

<i>SERPINE1</i> DNA Methylation Levels Quantified in Blood Cells at Five Years of Age Are Associated with Adiposity and Plasma PAI-1 Levels at Five Years of Age

Plasminogen activator inhibitor (PAI-1) expression has been associated with a higher risk of development of obesity. DNA methylation (DNAm) is an epigenetic mechanism regulating gene transcription and likely involved in the fetal programming of childhood obesity. Our study aimed to assess the associ...

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Bibliographic Details
Main Authors: Amelie Taschereau, Véronique Desgagné, Sabrina Faleschini, Renée Guérin, Catherine Allard, Patrice Perron, Marie-France Hivert, Luigi Bouchard
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
obesity
PAI-1
epigenetics
childhood
Online Access:https://www.mdpi.com/1422-0067/23/19/11833

Internet

https://www.mdpi.com/1422-0067/23/19/11833

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