Association between Alzheimer’s disease pathogenesis and early demyelination and oligodendrocyte dysfunction

Association between Alzheimer’s disease pathogenesis and early demyelination and oligodendrocyte dysfunction

The APPSwe/PSEN1dE9 (APP/PS1) transgenic mouse model is an Alzheimer’s disease mouse model exhibiting symptoms of dementia, and is commonly used to explore pathological changes in the development of Alzheimer’s disease. Previous clinical autopsy and imaging studies suggest that Alzheimer’s disease p...

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Bibliographic Details
Main Authors: Yu-Xia Dong, Hui-Yu Zhang, Hui-Yuan Li, Pei-Hui Liu, Yi Sui, Xiao-Hong Sun
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; Alzheimer′s disease; APP/PS1 mice; Morris water maze test; corpus callosum; demyelination; oligodendrocytes; myelin basic protein; monocarboxylic acid transporter 1; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=5;spage=908;epage=914;aulast=Dong

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=5;spage=908;epage=914;aulast=Dong

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