Rapamycin nanoparticles improves drug bioavailability in PLAM treatment by interstitial injection

Abstract Background Pulmonary lymphangiomyomatosis (PLAM) is a rare interstitial lung disease characterized by diffuse cystic changes caused by the destructive proliferation of smooth muscle-like cells or LAM cells. PLAM is more common in young women than other people, and a consensus is lacking reg...

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Bibliographic Details
Main Authors: Yahong Shi, Chuqiao Jiao, Xi Lu, Yifeng Nie, Xiang Li, Dong Han
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Online Access:https://doi.org/10.1186/s13023-022-02511-6